In Auckland, he joined The Embers on keyboards and then formed the Mike Perjanik Group, the in-demand studio band who backed touring stars and local musicians, including The Chicks (whom he named), Dinah Lee and Ray Columbus. It was Perjanik that discovered the young Maria Dallas and arranged for Viking Records’ Ron Dalton to sign her.
He played on and arranged almost every hit from the Viking Records stable in the mid 60s.
The inevitable move to Sydney in 1966 for residencies at Sydney's Coogee Bay Hotel and Latin Quarter in 1967 heralded an even more successful and multi-tiered career in Australia, where he performed as The Mike Perjanik Complex and was made A&R manager and in-house producer for EMI Australia’s Columbia label, steering successful pop and country rock group The Flying Circus, led by New Zealander Doug Rowe, to success.
In the 1970s, he was part of studio supergroup Patch and he recorded Australian star Richard Clapton. Mike Perjanik produced a constant stream of music soundtracks for hundreds of commercials, TV shows and movies, including the Australian cast recording of Jesus Christ Superstar in 1972.
His Mike Perjanik Orchestra also contributed the Renee Geyer sung theme music for soap opera Restless Years in the 1970s and A Country Practice and Home and Away in the 1980s.
A legend in the Australasian music community, he is a long-time board member of the Australasian Performing Rights Association and was its chairman until 2013.